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Detailed information of PINWORM
PINWORM
DEFINITION:
A nematode which infects the intestines and causes perianal
irritation.
EPIDEMIOLOGY:
- incidence: 5-15% of the population
- age of onset:
- any age with peak between 5-14 years of age
- risk factors:
- preschool and school-age children
PATHOGENESIS:
- pinworm (Enterobius vermicularis) eggs are ingested and
migrate to the duodenum where they hatch, mature, and then
travel to the cecum; the adult females emerge at night through
the anus and deposit their eggs in the perianal region then die;
the eggs stick to the skin and cause perianal pruritis ->
scratching -> accumulation of the eggs under the fingernails ->
autoinfection and spread
- the eggs may also fall off the skin into the underclothing,
pajamas, or sheets where they remain viable for 3-4 weeks
- the eggs may be acquired by direct contact with contaminated
areas but to be infectious the eggs must be swallowed
- man is the only natural host to pinworms
- the pinworms appear as 1 cm long, white, thread-like worms
while the ova are asymmetric with a flattened side and measure
30 x 60 um
CLINICAL FEATURES:
2. Other Manifestations
INVESTIGATIONS:
- apply adhesive cellophane tape to the perianal region early
in the morning upon awakening -> apply the tape to a glass slide
and look for the eggs under a low power microscope
MANAGEMENT:
- all household members should wash their hands after using
the toilet, changing diapers, and while preparing or eating food
- trim fingernails of all those affected
2. Medical
- drug of first choice
- 100 mg po once then again after 2 weeks
- may treat all household members
- interfere with larval development
- contraindications:
- hypersensitivity to the drug
- children less than 2 years of age (may cause seizures in
children less than 1 year of age)
2. Pyrantel Pamoate (Combantrin)
- drug of second choice
- 11 mg/kg po once then again after 2 weeks
- may treat all household members
- do not use in children less than 1 year of age
REFERENCES:
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Pediatric Database - PINWORM
Pediatric Organization - Pedbase [at] Gmail.com