OTITIS MEDIA

 

OTITIS MEDIA

 

DEFINITION:

Infection of the middle ear.

EPIDEMIOLOGY:

  • incidence: ?
  • age of onset:
    • any
  • risk factors:
    • craniofacial malformations
    • congenital disorders

PATHOGENESIS:

1. Background

1. Types of Otitis Media (OM)

1. Acute Otitis Media (AOM)

  • painful middle ear infection associated with toxicity
  • natural history of untreated cases
    • otalgia with fever +/- toxicity lasts from hours to 2-3 days then the tympanic membrane ruptures spontaneously with the symptoms disappearing - ear discharges pus through a small hole for 3 days which then closes and heals over - the remaining middle ear effusion disperses down the eustachian tube over the next 3 months

2. Otits Media with Effusion (OME)

  • painless middle ear infection not associated with toxicity
  • also called chronic serous otitis media
  • may be acute (<3 weeks), subacute (3 weeks-3 months), or chronic (>3 months)

2. Organisms (% of cases)

  • Strep. pneumoniae (27-52%)
  • H. influenzae* (16-52%)
  • Moraxella catarrhalis+ (2-15%)
  • Staph. aureus (0-16%)
  • Strep. pyogenes (0-11%)

     

  • * 15-33% of strains produce beta-lactamase
  • + 66-85% of strains produce beta-lactamase
  • CLINICAL FEATURES:

    1. Acute Otitis Media

    1. Symptoms

    • rapid onset of ear pain (otalgia) with fever +/-
      • irritability
      • vomiting
    • rapid onset of purulent discharge through a tympanotomy tube
    • longstanding tympanic membrane perforation

    2. Signs

    • erythematous and opaque tympanic membrane ™
    • TM immobile on pneumatic otoscopy

    3. Complications (in 5-15% of untreated cases)

    • acute labyrinthitis
    • acute mastoiditis
    • acute meningitis
    • lateral sinus thrombosis
    • persistent TM perforation
    • temperal lobe abscesses

    2. Otitis Media with Effusion

    1. Symptoms

    • feeling of fullness in the ears (plugged) but painless

    2. Signs

    • TM red, yellow, white, purple, and/or opaque
    • TM immobile on pneumatic otoscopy
    • effusion may be serous, mucoid, or purulent

    INVESTIGATIONS:

    1. For Hearing Loss

    • see file on "Hearing Loss"
      • Behavioural Observational Audiometry (BOA)
      • Tympanometry (Impedance Audiometry)
      • Brainstem Auditory-Evoked Responses (BAER)

    MANAGEMENT:

    1. Supportive

    • 85-95% of OM will resolve spontaneously without treatment but there is an increased incidence of complications if no medications are used
    • tylenol 15 mg/kg/dose q4h prn for analgesia
    • cleaning out of ear wax
      • 5 capsules of colace powder (100 mg/capsule) into 45 cc of normal saline; 3 drops in each ear tid x 3 days

    2. Antibiotics

    1. Amoxicillin (Amoxil)

    • 25 mg/kg/day po tid
    • 10-15% of organisms will be resistant to amoxil

    2. Trimethoprim-Sulfamethoxazole (Septra)

    • 6 mg trimethoprim/kg/day + 30 mg sulfamethoxazole/kg/day po bid
    • ineffective against Strep. pyogenes
    • side effects: blood dyscrasias, aplastic anemia due to sulfa component

    3. Amoxicillin/Clavulanate (Clavulin)

    • 50 mg/kg/day po tid
    • side effects: diarrhea

    4. Erythromycin Ethylsuccinate-Sulfisoxazole Acetyl (Pediazole)

    • 50 mg/kg/day (erythromycin component) po qid
    • side effects: blood dyscrasias, aplastic anemia due to sulfa component

    5. Topical Antibiotics

    1. Garasone Otic Preparation

    • topical corticosteroid + gentamicin
    • 3-4 drops into affected ear tid as long as discharge is present
    • indications: discharging tympanotomy tube, permanent tympanic membrane perforation

    3. Acute OM

    • antibiotic x 10 days with follow-up in 3 weeks if asymptomatic or after 72 hours if remains symptomatic
    • most children will still have a middle ear effusion after 10 days of therapy and 20% still have an effusion 2 weeks after the initiation of therapy; it may take 3 months for some effusions to clear

    4. Recurrent AOM

    1. More Than 2 Months Apart

    • antibiotic therapy as above with each attack treated as if it were the first

    2. Less Than 2 Months Apart

    • prophylactic antibiotics (use also if there are more than 3 attacks in a 6 month period):
    • 1. Septra at 50% treatment dosage po od
    • 2. Pediazole at 50% treatment dosage po od
    • 3. Amoxil at 50% treatment dosage po od
      • treat for 3-6 months in the fall and winter
      • treat for 6-8 weeks in the spring and summer
    • if an AOM develops during prophylactic therapy, discontinue the prophylactic antibiotic and switch to another anti-biotic at full strength, treat for 10 days, then resume prophylaxis

    5. Surgery

    1. Tympanotomy Tubes

    • indications for:
      • recurrent AOM and have failed prophylaxis
      • chronic OME (lasting >3 months) with hearing loss

    2. Adenoidectomy

    • indications for:
      • if tympanotomy tubes are required for a 3rd or 4th time

     

     

    Pediatric Database - OTITIS MEDIA

    Pediatric Organization - Pedbase [at] Gmail.com