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Detailed information of LARYNGEAL HEMANGIOMA
LARYNGEAL HEMANGIOMA
DEFINITION:
A hemangioma within the larynx resulting in varying degrees of
upper airway obstruction.
EPIDEMIOLOGY:
- incidence: rare
- age of onset:
- 85% by 6 months of age (stridor)
- risk factors:
- cutaneous hemangiomas
- F > M
PATHOGENESIS:
- hemangiomas represent a hemartoma of blood vessel
development and can be found within any organ of the body
- laryngeal hemangiomas:
- usually subglottic
- asymmetrically located usually posteriorly
- usually asymptomatic at birth but may become problematic
during the early months of life due to enlargement
CLINICAL FEATURES:
- inspiratory and expiratory stridor
- worse with crying & upper respiratory tract infections
- hoarseness, harsh cry
- chronic cough
- dyspnea +/- respiratory distress
- upper airway obstruction
2. Others
- feeding difficulties +/- failure to thrive
3. Associated Findings
- 50% of patients also have cutaneous hemangiomas
INVESTIGATIONS:
- diagnostic
- hemangioma
- compressible, consistency of a firm sponge, covered with
normal mucosa
- biopsy may cause significant bleeding although tends to be
fibrotic
2. Imaging Studies
- asymmetric narrowing of the subglottic region
MANAGEMENT:
- respiratory support with severe or life-threatening upper
airway obstruction, i.e., intubation, tracheostomy
2. Medical
- high dose systemic steroids
- high response rate but coupled with side effects
- tend to recur with cessation of therapy
3. Surgery
- indications
- significant upper airway obstruction
- failure to regress spontaneously or after steroid therapy
- excision
- CO2 laser, cryotherapy, open excision, endoscopic excision
- side effects include hemorrhage and postoperative scarring
and stenosis
4. Prognosis
- natural history is one of growth over 6-18 months followed
by spontaneous regression
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Pediatric Database - LARYNGEAL HEMANGIOMA
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