LARYNGEAL HEMANGIOMA

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    LARYNGEAL HEMANGIOMA

     

    DEFINITION:

    A hemangioma within the larynx resulting in varying degrees of upper airway obstruction.

    EPIDEMIOLOGY:

    • incidence: rare
    • age of onset:
      • 85% by 6 months of age (stridor)
    • risk factors:
      • cutaneous hemangiomas
      • F > M

    PATHOGENESIS:

    1. Background

    • hemangiomas represent a hemartoma of blood vessel development and can be found within any organ of the body
    • laryngeal hemangiomas:
      • usually subglottic
      • asymmetrically located usually posteriorly
      • usually asymptomatic at birth but may become problematic during the early months of life due to enlargement

    CLINICAL FEATURES:

    1. Respiratory Manifestations

    • inspiratory and expiratory stridor
      • worse with crying & upper respiratory tract infections
    • hoarseness, harsh cry
    • chronic cough
    • dyspnea +/- respiratory distress
    • upper airway obstruction

    2. Others

    • feeding difficulties +/- failure to thrive

    3. Associated Findings

    • 50% of patients also have cutaneous hemangiomas

    INVESTIGATIONS:

    1. Direct Laryngoscopy

    • diagnostic
    • hemangioma
      • compressible, consistency of a firm sponge, covered with normal mucosa
    • biopsy may cause significant bleeding although tends to be fibrotic

    2. Imaging Studies

    1. Neck X-Ray

    • asymmetric narrowing of the subglottic region

    MANAGEMENT:

    1. Supportive

    • respiratory support with severe or life-threatening upper airway obstruction, i.e., intubation, tracheostomy

    2. Medical

    • high dose systemic steroids
      • high response rate but coupled with side effects
      • tend to recur with cessation of therapy

    3. Surgery

    • indications
      • significant upper airway obstruction
      • failure to regress spontaneously or after steroid therapy
    • excision
      • CO2 laser, cryotherapy, open excision, endoscopic excision
      • side effects include hemorrhage and postoperative scarring and stenosis

    4. Prognosis

    • natural history is one of growth over 6-18 months followed by spontaneous regression

     

     

    Pediatric Database - LARYNGEAL HEMANGIOMA

    Pediatric Organization - Pedbase [at] Gmail.com