PEDBASE.org - The Pediatric Database - Detailed information of ENTEROADHERENT COLITIS

ENTEROADHERENT COLITIS

DEFINITION:

A bacterial infection of the colon caused by Enteroadherent E. coli (EAEC) resulting in a secretory diarrhea.

EPIDEMIOLOGY:

incidence: ?
risk factors:
- age: ?
- season: ?
- route: indirect: food, water (large inoculum needed)
- environ: ?
incubation period: ?

PATHOGENESIS:

1. Background

Enteroadherent E. coli is a gram negative rod
- serotypes ? (not a well studied pathogen)
- do not produce enterotoxins, enterocytotoxins, invade cells or possess EAF genes
- the nature of the bacterial products that cause fluid loss after EAEC adherence (diffuse or local) is unknown

CLINICAL FEATURES:

1. Diarrhea

significant amounts of stool with dehydration is common
grossly bloody stools are infrequent
associated symptoms: fever and nausea/vomiting are uncommon

2. Complications

chronic persistent diarrhea

INVESTIGATIONS:

1. Stool

culture

2. Biopsy

Pathology - not characterized in humans yet

MANAGEMENT:

1. Supportive

oral rehydration fluid (ORF) or intravenous rehydration

Pediatric Database - ENTEROADHERENT COLITIS

Pediatric Organization - Pedbase [at] Gmail.com