CONSTIPATION
DEFINITION:
The infrequent passage of stool.
EPIDEMIOLOGY:
- incidence: common
- age of onset:
- risk factors:
- see differential diagnosis
DIFFERENTIAL DIAGNOSIS:
- introduction of cow's milk
- inadequate fluid intake
- undernutrition
- high CHO and/or protein diet
- low fibre diet
2. Organic
- Diabetes Insipidus/Mellitus
- Fanconi Syndrome
- Idiopathic Hypercalcemia
2. CNS Lesions
- hypotonia (Benign Congenital Hypotonia)
- hypertonia (Cerebral Palsy)
- Infectious Polyneuritis/Poliomyelitis
- myelodysplasias
3. Gastrointestinal Anomalies
- Hirschsprung Disease
- anorectal stenotic lesions, strictures, fissures
- masses (intrinsic, extrinsic)
- anterior anal displacement
4. Others
- Hypothyroidism
- Prune-Belly Syndrome
3. Social/Medical
- "psychogenic constipation" - inadequately managed acute
problem
- coercise toilet training
- at school or camp
HISTORY:
- history of drugs (diuretics, antidepressants,
antispasmodics)
- constipation since birth (Hirschsprung Disease)
- concurrent bladder incontinence or abnormal anal tone (neurologic)
- hypothyroidism (dry skin, lethargy, slowing growing hair and
nails)
- assess height for short stature (can't touch floor)
- 99% of constipation is idiopathic
- look for a precipitating event (anal fissure)
CLINICAL FEATURES:
- constipation +/- abdominal pain
- complications:
- overflow incontinence with fecal soiling ("diarrhea")
- impaction with chronic dilatation
- UTI +/- vesicoureteral reflux
- intestinal obstruction
INVESTIGATIONS:
- abdominal x-rays may show rectal/rectosigmoid impaction and
a rectosigmoid index of < 1 (normal > 1)
2. Sigmoidoscopy
- with biopsy for Hirschrung Disease
MANAGEMENT:
- bran - oat, wheat
- psyllium - Metamucil, ProDiem
2. Osmotics
- magnesium - Milk of Magnesia, Epsin Salts
- phosphate - fleet enemas
- sugars - lactulose, sorbitol (gas, acidic stool)
- PEG - Go Litely
3. Stimulants
- phenolphthalein
- Senna, aloe, rhubarb
- castor oil
- bisacodyl
4. Stool Softeners
5. Lubricants
6. Enemas
-
Note: In the treatment of constipation in children,
there appears to be no role for stimulants, stool softeners,
lubricants, or enemas.
2. Management in Children
1. Rule out organic causes
2. Explain pathophysiology to family and patient
- draw out GI system and explain how stool is formed
- explain mechanism of constipation
- use analogy of boxcars
- use "I gotta go valve" and "not now valve"
- explain the 3 steps needed to correct the constipation
- no quick fix and in for the long haul with follow ups
- compliance is vital so fun foods are important
- parents, doctor, and child must have a health attitude
- may keep a stool diary to be reviewed on follow-up
3. Phase I - Clean Out Phase:
- to empty the bowel from above or below
1. Polyethylene Glycol (PEG)
- 2-4 litres over 2-3 days
- mix with Tropical Punch Kool-aid
- 5 scoops of Kool-aid to 1 litre of PEG
- will come out the same colour as flavoured PEG
- PEG is not thirst quenching so child will continue to
drink throughout the day
- try to buy in 1 litre jugs
- may also mix with frozen orange juice
- will be an initial liquid phase -> solid phase -> then
another liquid phase or
2. Hypertonic Phosphate Enemas
- three times over 36-48 hours
4. Phase II - Maintenance (Training) Phase:
- to allow the bowel to return to normal size
1. Milk of Magnesia (MM)
- 1 tbsp. po bid -> qid
- enough to give 1-2 loose stools per day everyday x 1
month
- may start during initial Clean Out Phase
- give between meals to avoid fat-soluble vitamin
absorption problems
- comes in many different flavours and
2. Oat Bran
- 2/3 cup oatbran + 1 cup of water
- microwave at 100% x 2 min + at 20% x 10 min
- add brown sugar, milk, strawberry cow, peaches, etc. or
3. Metamucil plain or ProDiem plain
- 1 tbsp. po od
- add Metamucil to peanut butter and jam sandwiches,
soups, mashed potatoes
- may make homemade jams with psyllium instead of pectin
- sprinkle ProDiem on Ice Cream or puddings
- sit on toilet with proper foot support for 5 minutes
after breakfast and after the evening meal (gastrocolic
reflex)
5. Phase III - Tapering Phase:
- reduce MM by 20% monthly
- follow-up:
- should see improvement in appetite, activity and school
performance
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