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Detailed information of CHRONIC BRONCHITIS
CHRONIC BRONCHITIS
DEFINITION:
A chronic inflammatory disease of the bronchi caused by chronic
bronchial irritation characterized by cough and chest pain.
EPIDEMIOLOGY:
- incidence: ?
- age of onset:
- childhood -> adolescence (chronic cough)
- risk factors:
- allergies
- agents causing chronic bronchial irritation:
- air pollution (car exhausts, industrial fumes)
- smoking (tobacco, marijuana)
- wood-burning stoves
PATHOGENESIS:
- existence of this entity is questionable
- usually associated with an underlying cause:
- immunodeficiencies
- decreased mucociliary clearance
- CF, Ciliary Dyskinesia Syndrome
- chronic respiratory diseases
- asthma, bronchiectasis, environmental disease, upper
airway infection
- difference between this entity and asthma is that the former
is usually associated with expectorate and chest soreness
CLINICAL FEATURES:
- frequently recurring
- usually with expectorate with "casts"
- worse at night
2. Others
- chest soreness
- chronic wheezing
INVESTIGATIONS:
- large solid hypereosinophilic mucoid masses
- contain metaplastic bronchial epithelium
- contain inflammatory cells & noncellular material
MANAGEMENT:
- treat underlying causes, i.e., asthma
- treat allergies
- avoid irritants, i.e., cigarette smoke
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Pediatric Database - CHRONIC BRONCHITIS
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